Evidence-Based Practices for Substance Use Care

Citation: Cioffi, C. C. (2025). Caring for People with Substance Use Disorders: Evidence-Based Practices.

When it comes to supporting people with substance use disorders, research shows what works—and what doesn’t. This snapshot highlights key takeaways from decades of studies, offering practical insights for programs, providers, and policymakers.

What You’ll Learn in This Blog

• Which treatments actually improve outcomes

• Practices that reduce harm and support recovery

• Approaches that are not supported by evidence

What the Evidence Says

✅ Effective treatments include:

• Medications for opioid use disorder

• Contingency management (financial incentives)

• Peer support and harm reduction

• Long-term treatment (3+ months)

🚫 Less effective or harmful approaches:

• Involuntary treatment

• Short residential stays without follow-up

• Fear-based prevention

📊 For more data and impact summaries, check out the infographic linked below.